Table 2.
Characteristics of studies included in the meta-analysis.
| Author | Year | Country |
Type of diabetes |
Men (%) |
Mean age (year) |
Duration of diabetes (year) | Mean BMI | Number of participants | Mean HbA1c value (%) | Method for identifying HP infection | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HP infected | HP non-infected | HP infected | HP non-infected | |||||||||
| Vafaeimanesh et al. [24] | 2014 | Iran | T2DM | 36.0 | 52.5 | 7.4 | 29.0 | 139 | 82 | 8.11 | 8.08 | HP-specific IgG using EIA |
|
| ||||||||||||
| Senmaru et al. [16] | 2013 | Japan | T2DM | 58.9 | 66.3 | 15.1 | 22.8 | 187 | 146 | 7.4 | 7.3 | HP-specific IgG using EIA |
|
| ||||||||||||
| El-Eshmawy et al. [22] | 2011 | Egypt | T1DM | 44.5 | 19.4 | 7.3 | NA | 128 | 34 | 8.3 | 6.8 | HP-specific IgA and IgG using EIA |
|
| ||||||||||||
| Tanriverdi [15] | 2011 | Turkey | T2DM | 52.7 | 55.4 | 2.9 | 28.2 | 53 | 40 | 6.9 | 6.1 | Biopsy |
|
| ||||||||||||
| Fernandini-Paredes et al. [11] | 2008 | Chile | T2DM | 46.7 | 52.8 | 8.2 | NA | 49 | 26 | 7.7 | 7.3 | [13C]urea breath test and biopsy |
|
| ||||||||||||
| Demir et al. [12] | 2008 | Turkey | T2DM | 32.2 | 52.0 | 6.1 | NA | 87 | 54 | 7.9 | 8.7 | Biopsy |
|
| ||||||||||||
| Hamed et al. [18] | 2008 | Egypt | T1DM and T2DM | 48.8 | 47.5 | 9.2 | 28.8 | 68 | 12 | 8.1 | 8.3 | HP-specific IgG using EIA |
|
| ||||||||||||
| Gulcelik et al. [13] | 2005 | Turkey | T2DM | 30.8 | 51.9 | 6.9 | 26.0 | 59 | 19 | 8.2 | 7.9 | Biopsy |
|
| ||||||||||||
| Candelli et al. [19] | 2003 | Italy | T1DM | 54.5 | 14.8 | 6.6 | 20.9 | 34 | 87 | 8.3 | 8.2 | [13C]urea breath test |
|
| ||||||||||||
| Colombo et al. [20] | 2002 | Italy | T1DM | 52.9 | 12.0 | 5.5 | NA | 41 | 97 | 7.8 | 8.6 | HP-specific IgA and IgG using EIA |
|
| ||||||||||||
| Ko et al. [14] | 2001 | China | T2DM | 46.0 | 49.9 | 6.2 | NA | 32 | 31 | 8.1 | 8.4 | Biopsy |
|
| ||||||||||||
| Arslan et al. [23] | 2000 | Turkey | T1DM | 40.9 | 12.6 | 10.7 | NA | 49 | 39 | 11.1 | 10.2 | HP-specific IgG using EIA |
|
| ||||||||||||
| Begue et al. [21] | 1999 | USA | T1DM | 50.7 | 11.3 | 3.6 | 20.0 | 11 | 60 | 14.9 | 11.8 | HP-specific IgG using EIA |
|
| ||||||||||||
| de Luis et al. [17] | 1998 | Spain | T1DM and T2DM | 50.4 | 60.2 | 16.1 | 28.8 | 53 | 74 | 7.1 | 7.2 | HP-specific IgG using EIA |
Abbreviations: HP: Helicobacter pylori; EIA: enzyme immunoassay; IgA: immunoglobulin A; IgG: immunoglobulin G; T1DM: type 1 diabetes mellitus; T2DM: type 2 diabetes mellitus.