Table 1. Demographic information for stage IV colorectal cancer cases, 1996–2007, California Cancer Registry.
| Total | Operation | Non-operation | p value | |
|---|---|---|---|---|
| Number of patients (n (%)) | 11,716 (100) | 8,599 (73.4) | 3,117 (26.6) | <0.0001 |
| Sex (n (%)) | <0.0001 | |||
| Male | 6,419 (54.8) | 4,564 (53.1) | 1,855 (59.5) | |
| Female | 5,297 (45.2) | 4,035 (46.9) | 1,262 (40.5) | |
| Agea | <0.0001 | |||
| Median (years) | 61.0 | 61.0 | 61.0 | |
| Range (years) | 20–84 | 20–84 | 20–84 | |
| <70 years | 8,593 (73.3) | 6,354 (73.9) | 2,239 (71.8) | |
| ≥70 years | 3,123 (26.7) | 2,245 (26.1) | 878 (28.2) | |
| Year of diagnosis (n (%)) | <0.0001 | |||
| 1996–1999 | 3,542 (30.2) | 2,768 (32.2) | 774 (24.8) | |
| 2000–2003 | 3,775 (32.2) | 2,770 (32.2) | 1,005 (32.2) | |
| 2004–2007 | 4,399 (37.6) | 3,061 (35.6) | 1,338 (42.9) | |
| Histologic subtype (n (%)) | <0.0001 | |||
| Adenocarcinoma | 10,276 (87.7) | 7,456 (86.7) | 2,820 (90.5) | |
| Mucinous adenocarcinoma | 1,372 (11.7) | 1,140 (13.0) | 258 (8.3) | |
| Other | 68 (0.6) | 29 (0.3) | 39 (1.3) | |
| Histologic gradeb (n (%)) | <0.0001 | |||
| Well differentiated | 466 (4.6) | 322 (3.9) | 144 (7.4) | |
| Moderately differentiated | 6,490 (63.5) | 5,198 (62.9) | 1,292 (66.0) | |
| Poorly differentiated | 3,158 (30.9) | 2,656 (32.2) | 502 (25.6) | |
| Undifferentiated | 105 (1.0) | 85 (1.0) | 20 (1.0) | |
| Site of primary tumor (n (%)) | <0.0001 | |||
| Proximal and transverse | 4,607 (39.3) | 3,770 (43.8) | 837 (26.9) | |
| Descending | 514 (4.4) | 414 (4.8) | 100 (3.2) | |
| Sigmoid | 2,674 (22.8) | 2,195 (25.5) | 479 (15.4) | |
| Rectosigmoid | 1,121 (9.6) | 864 (10.1) | 257 (8.3) | |
| Rectum | 2,293 (19.6) | 1,164 (13.5) | 1,129 (36.2) | |
| Unknown | 507 (4.3) | 192 (2.2) | 315 (10.1) | |
| Type of surgeryc (n (%)) | <0.0001 | |||
| No surgery | 3,117 (26.6) | 0 | 3,117 (100) | |
| Local excision | 80 (0.7) | 80 (0.9) | 0 | |
| Partial colectomy | 3,941 (33.7) | 3,941 (45.9) | 0 | |
| Hemicolectomy | 3,420 (29.2) | 3,420 (39.8) | 0 | |
| Total/procto-colectomy | 985 (8.4) | 985 (11.5) | 0 | |
| Unknown colectomy | 170 (1.5) | 170 (2.0) | 0 | |
| Socioeconomic status (n (%)) | <0.0001 | |||
| First quintile | 1,524 (13.0) | 1,065 (12.4) | 459 (14.7) | |
| Second quintile | 2,161 (18.4) | 1,561 (18.2) | 600 (19.3) | |
| Third quintile | 2,457 (21.0) | 1,776 (20.7) | 681 (21.9) | |
| Fourth quintile | 2,726 (23.3) | 2,028 (23.6) | 698 (22.4) | |
| Fifth quintile | 2,848 (24.3) | 2,269 (25.2) | 679 (21.8) |
The table only includes patients who received chemotherapy and had no contraindication to surgical resection of the primary tumor
a
Age at diagnosis
b
Missing data, 1,842
c
Missing data, 5