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. 2014 May 27;9(5):e97153. doi: 10.1371/journal.pone.0097153

Figure 6. FGF2 hydration changes induced by Sm27 binding.

Figure 6

Upper panel: ratio of the normalized intensities observed for holo and apo FGF2 is reported as a function of the residue number as derived from ePHOGSY NOE spectra. Dotted lines delimit intensity variations beyond ±50% upon sm27 binding. Lower panel: Ratio of the mean residence time (MRT) per residue calculated for all atoms over the whole MD trajectories of apo and holo protein. Distance cut-off of 3.5 Å was used. Dashed gray line highlights the binding site regions.