Table 1. Human and mouse proteolytic networks created from all annotated proteases, inhibitors, and substrates.
Organism | Total Nodes | Largest Connected Component | Proteases with Substratesa | Inhibitors with Target Proteasesa | Edges |
Human | 1,230 | 1,183 | 244 | 41 | 4,905 |
Mouse | 1,393 | 1,377 | 88 | 47 | 3,852 |
Protease and inhibitor numbers refer to those with at least one annotated cleavage or inhibition, respectively, in MEROPS and TopFIND.