Table II.
Comparative demographics
| Indeterminate (n = 329) | Non-indeterminate (n = 374) | P value* | Non-indeterminate Non-APAP (n = 286) | P value† | |
|---|---|---|---|---|---|
| Age (years) | .0005‡ | .90‡ | |||
| Median | 3.7 | 8.2 | 3.9 | ||
| 25%, 75% | 1.0, 9.5 | 0.7, 14.7 | 0.2, 12.9 | ||
| Min, max | 0.0, 18.0 | 0.0, 18.0 | 0.0, 18.0 | ||
| Male | 180 (54.7%) | 176 (47.1%) | .04§ | 158 (55.2%) | .89§ |
| Total bilirubin at presentation (mg/dL) | .001‡ | <.0001‡ | |||
| No. | 306 | 343 | 257 | ||
| Median | 14.2 | 5.0 | 8.1 | ||
| 25%, 75% | 6.1, 20.2 | 2.3, 13.7 | 3.2, 15.7 | ||
| Min, max | 0.2, 43.1 | 0.2, 59.5 | 0.2, 59.5 | ||
| AST at presentation (IU/L) | .19‡ | .001‡ | |||
| No. | 315 | 356 | 269 | ||
| Median | 1716 | 1611 | 866 | ||
| 25%, 75% | 519, 3321 | 334, 4171 | 215, 2956 | ||
| Min, max | 17, 710 000 | 11, 27 312 | 11, 14 312 | ||
| Encephalopathy 3 or 4 at presentation|| | 40 (13.0%) | 49 (13.9%) | .73§ | 37 (14.0%) | .73§ |
| Outcome for the first 21 days | <.0001§ | <.0001§ | |||
| Died | 31 (9.4%) | 57 (15.2%) | 54 (18.9%) | ||
| Transplantation | 146 (44.4%) | 69 (18.5%) | 64 (22.4%) | ||
| Alive | 152 (46.2%) | 248 (66.3%) | 168 (58.7%) |
*
P value to compare indeterminate group with non-indeterminate group.
†
P value to compare indeterminate group with non-indeterminate non-APAP group.
‡
From Wilcoxon rank-sum test.
§
From Pearson χ2 test.
||
Number of patients missing coma scores at presentation: indeterminate, 21, non-indeterminate 22 APAP 1.