Levels of SMOX protein, DNA damage, and apoptosis in ImSt Egfr−/− cells. WT and Egfr−/− Imst cells were co-cultured with H pylori 7.13 for 24 hrs. (A and B) Western blotting for pEGFR, EGFR, SMOX, and β-actin. (C and D) Levels of SMOX and 8-oxoguanosine, and representative histograms, respectively, by flow cytometry. (E) Percentage of cells that are 8-oxoguanosinehigh (left), active caspase-3high (middle), and 8-oxoguanosinehigh, active caspase-3low (right). (F) Representative dot plots. In C and E, **P < .01, ***P < .001 vs uninfected WT control; §P < 0.05, §§P < .01 vs 7.13-infected WT. n=3 experiments in duplicate.