Table 1.
A list of known functions for histone variants in the eukaryotic genome
| Histone variant | Function | Conserved? |
|---|---|---|
| CENP-A/CID/cse4 | Epigenetic marker of the centromere | Yes |
| H3.3 | Transcription | Yes |
| H2A.Z/H2AV | Transcription/double strand break repair | Yes |
| H2A.X | Double strand break repair/meiotic remodeling of sex chromosomes | Yes |
| macroH2A | Gene silencing/X chromosome inactivation | Yes |
| H2A.Bbd | Epigenetic mark of active chromatin | Yes |
| H3.Z | Regulation of cellular response to outside stimuli | No |
| H3.Y | Regulation of cellular response to outside stimuli | No |