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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Eur J Pharm Biopharm. 2013 Dec 4;87(1):187–196. doi: 10.1016/j.ejpb.2013.11.008

Table 2.

Summary of IC50 Values of Gemcitabine, P-Gem, mP-Gem, DACH Platinum, P-DACH Pt, mP-PGFLG-DACH platinum against A2780 cells for 72 h.

Drugs Mw (kDa) IC50 (nM)
Gemcitabine.HCl 0.3 6.17 ± 0.45 graphic file with name nihms551768t1.jpg *
P-GEM 32 9.22 ± 1.73
mP-GEM 139 6.53 ± 1.56
DACH Platinum 0.195 161.3 ± 14.6 graphic file with name nihms551768t2.jpg graphic file with name nihms551768t3.jpg*
P-DACH Pt 38 1340.7 ± 81.9
mP-DACH Pt 365 1592.3 ± 272.4

IC50 is the concentration that inhibits 50% cells growth in treated cells when compared to control cells. Mw is the weight average molecular weight. Values are mean ± SD of at least three independent experiments.

*

represents the statistically significant difference between the two groups (one-way ANOVA, p<0.01).