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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Mamm Genome. 2014 Jan 22;25(0):244–252. doi: 10.1007/s00335-014-9504-4

Fig. 3.

Fig. 3

Ept7 affects induction of pituitary growth in male rats by diethylstilbestrol. DES was administered through continuous release from Silastic™ implants that were inserted subcutaneously when the rats were 9 weeks of age. Sham treated control rats received empty implants. The rats were euthanized 12 weeks later. Pituitary weight was evaluated as an indicator of the effects of DES on pituitary growth resulting from lactotroph hyperplasia. Each data bar represents the mean ± standard error of the mean, n = 4–6 rats per group. 1, p ≤ 0.05 for comparison between sham treated and DES treated rats of same strain. 2, p ≤ 0.05 for comparison to ACI rats that received the same treatment. 3, p ≤ 0.05 for comparison to BN rats that received the same treatment