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. Author manuscript; available in PMC: 2015 May 22.
Published in final edited form as: Mol Cell. 2014 Apr 17;54(4):601–612. doi: 10.1016/j.molcel.2014.03.024

Figure 5. Kin28 depletion affects SAGA-dependent transcription more than TFIID-dependent transcription.

Figure 5

(A, B) Cumulative frequency plots of transcription (Pol II occupancy) changes at SAGA- and TFIID-dependent genes (Huisinga and Pugh, 2004) upon Kin28 depletion in the Kin28-AA strain or inactivation of Kin28 kinase activity in the kin28-as strain.

(C) Cumulative frequency plots of TFIIB occupancy changes at SAGA- and TFIID-dependent genes upon Kin28 depletion by anchor-away.

(D) Pol II (blue and red lines) and Kin28-FRB (black line) ChIP-seq binding profiles across promoter regions (+/− 500 bp from ATG) of active SAGA- and TFIID-dependent genes in the Kin28-AA strain before and after Kin28 depletion.

(E) Spt16 ChIP-seq binding profiles were plotted for the same regions, as in (D).

See also Figures S5 and S6.