MM-6 cells were treated with 1 ng/ml LPS, 25 µg/ml amine-terminated generation 6 poly(amidoamine) dendrimers, or a combination of both LPS and G6-NH2 (G6-NH2 + LPS). PCA is calculated as a percentage of that induced by the positive control. Shown is the mean response ± standard deviation of three independent experiments (n = 3).
G6-NH2: Generation 6 amine-terminated polyamidoamine dendrimer; LPS: Lipopolysaccharide; PC: Positive control (lipopolysaccharide; 10 µg/ml); PCA: Procoagulant activity.