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(Left) Side view of the homology model for the α3β2-nAChR (ribbon) depicting the overall structural components of the transmembrane ligand-gated ion channel. (Right) Side view of the subunit dimer complex composed of a primary (+) α and a complementary (−) β subunit designating specific loop regions including the C-loop (i.e., where ACh binds) and the Cys-loop (i.e., characteristic of this family of channels).
