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. 2014 May 28;34(22):7562–7574. doi: 10.1523/JNEUROSCI.5616-12.2014

Figure 6.

Figure 6.

CDPPB did not alter extinction-induced decreases in eAMPA currents in PrL slices. Rats were trained to self-administer ethanol using an ethanol pre-exposure paradigm and then administered vehicle or CDPPB during abstinence (ABST) or extinction training (EXT). A, Whereas extinction training significantly decreased the amplitude of eAMPA currents in the PrL cortex when measured at a holding potential of −80 mV (p = 0.011; indicated by an asterisk above the bar), daily injections of CDPPB did not alter evoked AMPA currents in either the ABST or EXT groups (n = 6). B, C, In the PrL cortex, there were no differences between vehicle and CDPPB in the input-output relationship of eAMPA currents in either the ABST or EXT groups. D, In the IfL cortex, neither extinction training nor CDPPB altered the amplitude of eAMPA currents measured at a holding potential of −80 mV (n = 6). E, F, The input-output relationships of eAMPA currents were not significantly different between vehicle and CDPPB in either the ABST or EXT groups.