Figure 8.

Summary of KAR distribution and functional properties in macaque OFF cone bipolar cells. The five OFF-bipolar cell types are illustrated at the top, and their ganglion cell targets or putative targets are shown (i). (ii) ACET sensitivity data are shown in Figure 1. (iii) ATPA/Glu desensitization data are shown in Figures 1 and 5. (iv) Recovery from ATPA desensitization is shown in Figure 5. (v) GluK1 subunits were localized to DB2 and DB3b cells. The other cell types lack GluK1 and presumably express GluK2 and/or 3 subunits as their low-affinity subunits (Fig. 6). (vi) Neto1 was localized to DB1 dendrites (Fig. 7); and because it was not seen on DB2 and DB3b cells, we propose that the remaining Neto1 staining likely is present on FMB and DB3a cells. (vii) Prominent rebound tail currents have been observed in heteromeric KARs containing a high-affinity subunit in conjunction with the Neto1 accessory protein (Fisher and Mott, 2013). Rebound currents are shown in Figures 5 and 7. n.d., Not determined.