Skip to main content
. 2014 May 27;12:34. doi: 10.1186/1741-7007-12-34

Figure 3.

Figure 3

Mitochondrial dysfunction induces stress responses or mitophagy. Loss of mitochondrial electron transport chain function and/or misfolded proteins in mitochondrial matrix induces expression of genes through decreases in mitochondrial membrane potential. Sustained loss of mitochondrial membrane potential can invoke mitophagy, a process to eliminate dysfunctional mitochondria.