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. 2014 May 6;4(5):e389. doi: 10.1038/tp.2014.26

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Copyright © 2014 Macmillan Publishers Limited

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Profiles showing the mean BDNF mRNA levels (μCi g⁻¹) for schizophrenia (pink), depression (light blue), bipolar disorder (yellow) and normal controls (dark blue), as a function of distance from the pial surface (a) DLPFC, (c) ACC, (e) OFC. Percentages on the x axis refer to proportion of total cortical width occupied by specific lamina. Post hoc testing revealed (b) schizophrenia group with significantly less BDNF mRNA than controls in layers IV and V of DLPFC and (d) schizophrenia and depressed with significantly less BDNF mRNA than controls in layer VI of ACC. *P<0.05, **P<0.01.