Table 3.
Univariateanalysis of V3G-V5G and V3-V5
| |
V3G (cc) |
V4G (cc) |
V5G (cc) |
V3 (%) |
V4 (%) |
V5 (%) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean ± SD | p | Mean ± SD | p | Mean ± SD | p | Mean ± SD | p | Mean ± SD | p | Mean ± SD | p | |
|
leukoencephalopathy |
|
|
|
|
|
|
|
|
|
|
|
|
| Grade 0-1 |
204.94 ± 150.85 |
0.288 |
77.94 ± 67.47 |
0.316 |
34.12 ± 30.99 |
0.574 |
4.66 ± 3.40 |
0.102 |
1.77 ± 1.52 |
0.334 |
0.78 ± 0.71 |
0.609 |
| Grade 2 |
128.60 ± 80.62 |
|
51.08 ± 49.53 |
|
27.14 ± 24.85 |
|
3.00 ± 1.81 |
|
1.18 ± 1.12 |
|
0.63 ± 0.57 |
|
|
Number of lesions |
|
|
|
|
|
|
|
|
|
|
|
|
| <3 |
126.05 ± 115.60 |
0.017 |
39.06 ± 44.83 |
0.004 |
18.65 ± 17.00 |
0.010 |
2.94 ± 2.55 |
0.020 |
0.91 ± 0.98 |
0.004 |
0.44 ± 0.39 |
0.013 |
| ≥3 |
245.84 ± 136.82 |
|
104.24 ± 64.15 |
|
46.70 ± 32.90 |
|
5.57 ± 3.14 |
|
2.36 ± 1.47 |
|
1.05 ± 0.76 |
|
|
Maximum lesion volume |
|
|
|
|
|
|
|
|
|
|
|
|
| <3 cc |
94.13 ± 67.73 |
0.004 |
35.77 ± 27.52 |
0.006 |
15.35 ± 7.55 |
0.003 |
2.20 ± 1.42 |
0.001 |
0.83 ± 0.61 |
0.006 |
0.36 ± 0.17 |
0.004 |
| ≥3 cc |
238.73 ± 143.95 |
|
91.77 ± 70.05 |
|
42.49 ± 32.74 |
|
5.43 ± 3.24 |
|
2.08 ± 1.58 |
|
0.97 ± 0.75 |
|
|
Total volume of lesions |
|
|
|
|
|
|
|
|
|
|
|
|
| <7 cc |
108.74 ± 76.57 |
0.002 |
35.82 ± 31.48 |
0.002 |
15.43 ± 11.06 |
0.001 |
2.55 ± 1.75 |
0.003 |
0.83 ± 0.70 |
0.002 |
0.36 ± 0.25 |
0.002 |
| ≥7 cc |
264.39 ± 145.93 |
|
107.71 ± 68.56 |
|
50.15 ± 30.07 |
|
5.98 ± 3.30 |
|
2.44 ± 1.56 |
|
1.14 ± 0.74 |
|
| Total | 183.87 ± 138.15 | 70.53 ± 63.36 | 32.19 ± 29.16 | 4.21 ± 3.10 | 1.61 ± 1.43 | 0.74 ± 0.67 | ||||||
Abbreviations: VXG =. The volume of normal brain tissue receiving at least XGy per fraction during the SIB; VX =. The percentage volume of normal brain receiving at least XGy per fraction during the SIB; cc = cubic centimeter.