Table 1.
Percentage of VTT neurons tested with and responding to a specific number of pruritogens and/or partial pruritogens injected intradermally in the face
| No. of Pruritogens Tested | No. of Pruritogens Eliciting a Response |
|||||
|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
| ≥1 (N = 104) | 52% (n = 54) | 31% (n = 32) | 10% (n = 10) | 6% (n = 6) | 2% (n = 2) | 0% (n = 0) |
| ≥2 (N = 92) | 58% (n = 53) | 23% (n = 21) | 11% (n = 10) | 6% (n = 6) | 2% (n = 2) | 0% (n = 0) |
| ≥3 (N = 87) | 60% (n = 52) | 20% (n = 17) | 11% (n = 10) | 7% (n = 6) | 2% (n = 2) | 0% (n = 0) |
| ≥4 (N = 62) | 50% (n = 31) | 21% (n = 13) | 16% (n = 10) | 10% (n = 6) | 3% (n = 2) | 0% (n = 0) |
| ≥5 (N = 47) | 45% (n = 21) | 19% (n = 9) | 21% (n = 10) | 11% (n = 5) | 4% (n = 2) | 0% (n = 0) |
Percentages are calculated by dividing the number of neurons in which a specific number of pruritogens and/or partial pruritogens elicited a response (n) by the total number of neurons in which a specific number of pruritogens and/or partial pruritogens was tested (N). For example, in the 3rd column “23%” refers to the number of neurons in which 1 pruritogen elicited a response (n = 21) divided by the number of neurons in which ≥2 pruritogens were tested (N = 92). Data include neurons tested with the pruritogens serotonin, BAM8-22, chloroquine, cowhage, and/or the partial pruritogens histamine and capsaicin. VTT, trigeminothalamic tract.