Table 3.
Egger’s linear regression test to measure the funnel plot asymmetry*
| Groups |
Y axle intercept:
a
(95 % CI) |
|||||
|---|---|---|---|---|---|---|
| Overall | Controls in HWE | Caucasian | Asian | POAG (Caucasian) | POAG (Asian) | |
| ε2 vs ε3 |
−0.66(−3.09-1.77) |
−0.93(−3.39-1.54) |
−0.22(−3.69-3.23) |
−1.06(−6.79-4.66) |
0.03(−5.81-5.87) |
−1.68(−4.48-1.13) |
| ε2 carriers vs ε3ε3 |
−0.03(−2.36-2.29) |
−1.38(−4.14-1.38) |
0.55(−2.73-3.83) |
−0.50(−5.90-4.90) |
1.14(−4.80-7.08) |
−2.07(−7.60-3.46) |
| ε2ε2 vs ε3ε3 |
−0.94(−5.04-3.15) |
−0.94(−5.04-3.15) |
−3.15(−8.03-1.73) |
NA |
−2.28(−16.07-11.52) |
NA |
| ε4 vs ε3 |
2.81(−0.76-6.39) |
3.21(−0.14-6.56) |
−0.45(−3.63-2.73) |
7.63(0.14-15.12) |
−1.60(−6.29-3.08) |
7.26(2.85-11.66) |
| ε4 carriers vs ε3ε3 |
3.49(0.56-6.41) |
3.23(0.16-6.31) |
0.38(−2.34-3.11) |
7.73(3.29-12.18) |
0.35(−4.70-5.40) |
6.54(3.07-10.01) |
| ε4ε4 vs ε3ε3 | −2.15(−5.52-1.22) | −2.18(−6.29-1.93) | −2.35(−6.03-1.32) | 2.01(−1.14-5.15) | −2.26(−6.69-2.17) | NA |
*POAG: primary open angle glaucoma; HWE: Hardy-Weinberg equilibrium; vs: versus; CI: confidence interval; NA: not available.