Table 3.
Physiological parameters in patients with and without chronic bacterial colonisation
|
Non-cystic fibrosis bronchiectasis |
Cystic fibrosis |
|||
|---|---|---|---|---|
|
No chronic colonisation |
Chronic colonisation |
No chronic PsA colonisation |
Chronic PsA colonisation |
|
| (n = 26) | (n = 17) | (n = 25) | (n = 15) | |
| FEV1 (% pred.) |
86.1 (5.3) |
75.6 (4.9) |
69.7 (4.5) |
59.6 (4.5) |
| FVC (% pred.) |
101.7 (4.6) |
87.5 (4.1)# |
86.9 (3.6) |
80.6 (5.5) |
| FEV1/FVC (%) |
68.6 (2.4) |
68.1 (2.4) |
67.1 (2.5) |
63.9 (2.5) |
| TLC (% pred.) |
95.3 (3.1) |
93.9 (4.0) |
- |
- |
| LCI |
10.02 (0.36) |
9.95 (0.57) |
12.29 (0.72) |
14.44 (0.85) |
| LCIvent |
1.42 (0.03) |
1.41 (0.05) |
1.59 (0.05) |
1.75 (0.05) |
| LCIds |
1.27 (0.02) |
1.26 (0.03) |
1.34 (0.03) |
1.49 (0.04)## |
| Scond (L‒1) |
0.058 (0.010) |
0.072 (0.010) |
0.122 (0.010) |
0.132 (0.018) |
| Sacin (L‒1) |
0.429 (0.053) |
0.288 (0.038) |
0.438 (0.070) |
0.611 (0.093) |
| Scond* (L‒1) |
0.102 (0.014) |
0.115 (0.016) |
0.284 (0.034) |
0.294 (0.051) |
| Sacin* (L‒1) | 0.412 (0.053) | 0.268 (0.041) | 0.376 (0.068) | 0.553 (0.092) |
PsA = Pseudomonas aeruginosa; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; TLC = total lung capacity; LCI = lung clearance index; LCIvent = specific ventilation inequality component of lung clearance index; LCIds = dead space component of lung clearance index. Data expressed as mean (standard error). Colonised and non-colonised groups within each disease cohort compared using Student’s T test. Significant differences between groups denoted #(p < 0.05) or ##(p < 0.01).