Table 1.
Relative abundance in percentage of major glycostructures detected on human-serum IgM and SM6 produced in different expression hosts
| GS1-3 | GS4-5 | |||||||||
| Structure | IgMhs | SM6PER | SM6wt | SM6∆XF | SM6sia | IgMhs | SM6PER | SM6wt | SM6∆XF | SM6sia |
| GnGn | 52 | 15 | ||||||||
| GnGnF | 11 | |||||||||
| MGnXF | 6 | |||||||||
| GnGnXF | 60 | |||||||||
| MNa | 16 | |||||||||
| GnAF | 7 | |||||||||
| AAF | 10 | |||||||||
| ANa | 7 | |||||||||
| ANaF | 35 | 30 | ||||||||
| ANaFbi | 33 | |||||||||
| NaNa | 17 | |||||||||
| NaNaF | 10 | |||||||||
| NaNaFbi | 8 | |||||||||
| ANaF+F | 10 | |||||||||
| ∑ other complex | 13 | 29 | 10 | 9 | 13 | 4 | 4 | 4 | 2 | |
| ∑ oligoman | 1 | 14 | 24 | 29 | 32 | 100 | 96 | 96 | 96 | 98 |
IgMhs: human-serum–derived IgM; ∑ other complex: sum of glycoforms present at levels below 5%; ∑ oligoman: oligomannosidic and hybrid glycans. The glycan structures are assigned using the ProGlycAn nomenclature (www.proglycan.com).