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. 2014 Apr 14;111(17):6401–6406. doi: 10.1073/pnas.1404205111

Fig. 2.

Fig. 2.

Effect of prophylactic administration of mCBMs in BALB/c mice given a lethal challenge with mouse-adapted A/California/04/2009 (H1N1) influenza virus. (A) (Upper) Survival and (Lower) weight changes of mice (n = 5) after a single intranasal dose of Vc4CBM (50, 250, or 500 µg), Vc2CBMTD (10, 50, or 250 µg), or Sp2CBMTD (10, 50, or 250 µg) given on day −1 before viral challenge. (B) (Upper) Survival curves for mice given the same single intranasal doses of one of the three biologics on day 0, immediately before viral challenge. (Lower) Corresponding weight-loss curves. Each value represents mean body weight ± SD for five mice.