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Exposure to BU-32 reduces the expression of inflammatory marker genes. Expression COX2, IL6 and TNFa inflammatory genes in RPMI8226, MM1S, MM1R, and U266 myeloma cell lines exposed to proteasome inhibitor, as evaluated by real-time RT-PCR. RT-PCR was done on RNA extracted from 24 h drug treated myeloma cell lines. Results are ± SD of three independent determination.
