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. 2014 Feb 25;289(15):10518–10529. doi: 10.1074/jbc.M114.552463

FIGURE 2.

FIGURE 2.

RAD17 and RAD24 exhibit a web of genetic interactions with nucleosome assembly factors upon DNA damage stress. A, CAC1, RTT106, and 9-1-1 genetic interactions in response to CPT, Zeocin, HU, and MMS. B and C, RAD17 (B) and RAD24 (C) exhibit synthetic interactions with histone mutants harboring mutations at lysine residues that are acetylated on newly synthesized histones. H35KR: H3K9, -14, -18, -23, -27R. Genetic interactions in response to CPT, Zeocin, HU, and MMS were assessed as described in Fig. 1B. The day after plating for which the recorded image was taken is reported below the image.