FIGURE 2.

A SAP97-AKAP-GluA1 protein complex forms early in conditioning and is delivered to PSD95 as shown by coimmunoprecipitation studies. A–F, analysis of the timing of the protein-protein interactions induced by conditioning evaluated in naïve, pseudoconditioned, and conditioned preparations that underwent training for the different time periods indicated is shown. Except for the GluA1-stargazin (D) association that failed to show conditioning-related changes, significant interactions were observed mainly after 15 min of conditioning. Input (naïve) and IgG lanes are also shown. *, significant differences from N.