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. 2014 Feb 10;289(15):10769–10784. doi: 10.1074/jbc.M113.515940

FIGURE 8.

FIGURE 8.

Downstream targets of TDP-43. Western blot analysis of brain lysates from 3- and 15-month-old mutants compared with controls showing decreased protein level for the Parkinson disease-related protein PARKIN (A) of about 70%. The autophagic marker Opa-1 was found to be elevated in 3-month-old and decreased in 15-month-old mutants (B). CD-36 protein was significantly reduced in old mutants as compared with controls (C). Error bars, S.E.