Table 4.
Results of Adjusteda Logistic Regression Models for Associations of Prenatal DDT and DDE Exposure With Overweight/Obese Status and Increased Waist Circumference at 9 Years of Age, Overall and by Child Sex, Center for the Health Assessment of Mothers and Children of Salinas Study, 2000–2010
| Outcome | Casesb | Total | Adjusted ORc | 95% CI | Child Sex |
P for Interaction | |||
|---|---|---|---|---|---|---|---|---|---|
| Male |
Female |
||||||||
| Adjusted ORc | 95% CI | Adjusted ORc | 95% CI | ||||||
| Overweight/ obesity |
|||||||||
| o,p′-DDT | 145 | 260 | 1.20 | 0.75, 1.92 | 2.51 | 1.00, 6.28 | 0.76 | 0.46, 1.25 | 0.02 |
| p,p′-DDT | 146 | 261 | 1.20 | 0.79, 1.81 | 2.11 | 1.00, 4.46 | 0.80 | 0.50, 1.27 | 0.03 |
| p,p′-DDE | 146 | 261 | 1.19 | 0.72, 1.99 | 1.97 | 0.94, 4.13 | 0.69 | 0.35, 1.37 | 0.04 |
| Increased waist circumference |
|||||||||
| o,p′-DDT | 121 | 260 | 1.20 | 0.77, 1.86 | 1.98 | 0.95, 4.11 | 0.88 | 0.53, 1.44 | 0.07 |
| p,p′-DDT | 122 | 261 | 1.31 | 0.88, 1.93 | 2.05 | 1.10, 3.82 | 0.92 | 0.58, 1.47 | 0.04 |
| p,p′-DDE | 122 | 261 | 1.31 | 0.79, 2.16 | 1.98 | 0.97, 4.04 | 0.83 | 0.43, 1.62 | 0.08 |
Abbreviations: CI, confidence interval; DDE, dichlorodiphenyldichloroethylene; DDT, dichlorodiphenyltrichloroethane; OR, odds ratio.
a All models were adjusted for maternal prepregnancy body mass index (weight (kg)/height (m)2) and time in the United States at birth.
b There were 70 male and 76 female overweight/obese cases and 48 male and 73 female cases with increased waist circumference.
c OR is for a 10-fold increase in exposure.