Table 2.
Factors Associated With Change in LDL-C Levels Over 6 Months After MI in the TRIUMPH Study, 2005–2008
| Factor | Change in LDL-C From Discharge to 6 Months |
|||||
|---|---|---|---|---|---|---|
| Adjusted for Patient Factors |
Adjusted for Patient Factors and Statin Therapy at Discharge |
|||||
| Estimate | 95% CI | P Value | Estimate | 95% CI | P Value | |
| Months since MI | <0.001 | |||||
| 1 | −13.2 | −15.5, −10.9 | NA | |||
| 6 | −7.9 | −10.7, −5.0 | NA | |||
| Statin use | <0.001 | |||||
| No statin at 1 month | NA | −5.0 | −12.0, 1.9 | |||
| No statin at 6 months | NA | −3.4 | −12.1, 5.3 | |||
| Low statin at 1 month | −3.1 | −8.2, 2.1 | ||||
| Low statin at 6 months | 1.7 | −4.7, 8.1 | ||||
| Moderate statin at 1 month | NA | −13.6 | −16.9, −10.3 | |||
| Moderate statin at 6 months | NA | −10.2 | −14.5, −6.0 | |||
| Intensive statin at 1 month | NA | −25.1 | −29.9, −20.3 | |||
| Intensive statin at 6 months | NA | −13.9 | −19.7, −8.0 | |||
| Age (per 10 years) | −3.3 | −5.0, −1.6 | <0.001 | −2.8 | −4.5, −1.1 | 0.001 |
| Male | −7.1 | −10.9, −3.2 | <0.001 | −6.8 | −10.7, −3.0 | <0.001 |
| White race | −0.2 | −4.5, 4.1 | 0.931 | −0.7 | −5.0, 3.6 | 0.747 |
| Married | −2.8 | −6.4, 0.9 | 0.135 | −2.4 | −6.0, 1.3 | 0.204 |
| Low social support | 3.7 | −0.9, 8.3 | 0.113 | 4.1 | −0.5, 8.6 | 0.081 |
| High school or greater education | −6.6 | −12.9, −0.2 | 0.044 | −6.6 | −13.0, −0.3 | 0.041 |
| Avoids health care because of cost | 4.3 | 0.3, 8.2 | 0.035 | 4.6 | 0.6, 8.5 | 0.023 |
| Hypertension | −5.4 | −9.2, −1.6 | 0.005 | −5.7 | −9.5, −1.9 | 0.003 |
| In-hospital bypass surgery | −4.6 | −10.9, 1.7 | 0.149 | −3.3 | −9.8, 3.2 | 0.314 |
| In-hospital angioplasty | −3.2 | −7.7, 1.2 | 0.157 | −3.2 | −7.7, 1.3 | 0.162 |
| Diabetes mellitus | 0.7 | −3.4, 4.8 | 0.738 | 0.5 | −3.7, 4.6 | 0.831 |
| Current/former smoking | 0.0 | −3.7, 3.6 | 0.990 | 1.1 | −2.6, 4.8 | 0.558 |
| Chronic lung disease | −4.0 | −11.0, 2.9 | 0.255 | −5.4 | −12.4, 1.5 | 0.124 |
| Prior heart failure | −4.5 | −11.1, 2.2 | 0.190 | −4.9 | −11.6, 1.8 | 0.152 |
| Chronic kidney disease | 0.7 | −4.1, 5.5 | 0.777 | 0.9 | −4.0, 5.7 | 0.729 |
| Cerebrovascular disease | 4.2 | −2.9, 11.2 | 0.840 | 2.6 | −4.5, 9.7 | 0.467 |
| Depression | −3.2 | −7.4, 0.3 | 0.145 | −3.1 | −7.4, 1.1 | 0.147 |
| Body mass indexa | 0.2 | −1.4, 1.7 | 0.840 | 0.4 | −1.1, 2.0 | 0.581 |
| ST elevation MI | −3.5 | −7.3, 0.3 | 0.068 | −3.3 | −7.1, 0.5 | 0.091 |
Abbreviations: CI, confidence interval; LDL-C, low-density lipoprotein cholesterol; MI, myocardial infarction; NA, not applicable; TRIUMPH, Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status.
a Weight (kg)/height (m)2.