Correlation between expression levels of SRC, HIF1α target genes, and proliferative marker gene, pcna, in clinical human UBC samples.
A, two representative UBC specimens for immunohistochemistry staining of SRC-3 and Glut1 in adjacent sections. Case 1, SRC-3 negative and Glut1 negative; case 2, positive nuclear staining of SRC-3 and positive membrane staining of Glut1. Bar, 100 μm. B, correlation between expression levels of SRC-3 and Glut1 in a cohort of human UBC specimens (n = 20, Spearman rank correlation coefficient). C and D, linear regression of src-3, HIF1α target genes (pgk1 and vegfa), and proliferative marker gene (pcna), using UBC samples from the GEO profiles database (GSE3167, n = 46).