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. 2014 Feb 28;289(16):11242–11252. doi: 10.1074/jbc.M113.537472

FIGURE 8.

FIGURE 8.

Far UV CD spectra of 16.0 μm Aβ1–40 in 20 mm Tris-HCl, pH 7.4, at 293 K is plotted as a function of time in the interval from 0 to 50 h (A). The first (B) and the second (C) spectral components of the far UV CD spectra of 16.0 μm Aβ1–40 in 20 mm Tris-HCl, pH 7.4, at 293 K are identified by singular value decomposition and plotted as a function of time in the interval from 0 to 50 h. The effect of BSBps on the far UV CD changes of Aβ1–40 is monitored at 198 and 215 nm. The changes at 198 nm (D) and at 215 nm (E) of the first and second spectral component, respectively, of 16 μm Aβ1–40 dissolved in 20 mm Tris-HCl, pH 7.4, are followed in the absence (full dots) and presence of a 12 m excess of Ac-LPFFD-NH2 (full triangles) from 0 to 3500 min and of Ac-LPFFN-NH2 (full squares) from 0 to 6800 min.