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. 2014 Mar 4;289(16):11272–11281. doi: 10.1074/jbc.M113.537175

FIGURE 1.

FIGURE 1.

The NADH binding motif in the proteasomal subunits. A, the predicted NADH binding consensus (GxGxxG) as determined by examining a large data set of resolved structures of protein complexes with NADH and by using the Meme motif discovery tool. B–F, the alignment of the NADH binding consensus containing proteasomal subunits Psmc1/Rpt2 (B), Psmd9/p27 (C), Psmd14/Rpn11 (D), Psmd3/Rpn3 (E), and Adrm1/Rpn13 (F) in various vertebrates. H. sapiens, Homo sapiens; F. pygmaeus, Flectonotus pygmaeus; C. porcellus, Cavia porcellus; M. mulatta, Macaca mulatta; C. familiaris, Canis familiaris; M. musculus, Mus musculus; R. norvegicus, Rattus norvegicus; B. taurus, Bos taurus; E. cabballus, Equus ferrus cabballus; M. domestica, Monodelphis domestica; O. anatinus, Ornithorhynchus anatinus; G. gallus, Gallus gallus; X. tropicalis, Xenopus tropicalis; T. rubripes, Takifugu rubripes; G. aculeatus, Gasterosteus aculeatus; T. nigroviridis, Tetraodon nigroviridis; O. latipes, Oryzias latipes; D. rerio, Danio rerio.