KCNQ2 channel tethers functional CK2.
A, immunoprecipitation (IP) showing selective binding of HA-tagged CK2α to KCNQ2-FLAG, but not to Kv1.2-FLAG or KCNQ3-FLAG. *, p < 0.05 by nonparametric ANOVA followed by Dunn's multiple comparisons test. IB, immunoblotting. Error bars show S.E. B, CK2 assay of immunoprecipitates from Kv1.2-FLAG or KCNQ2-FLAG. TBCA completely eliminated CK2 activity. **, p < 0.01 by Mann-Whitney test.