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. 2014 May 3;33(1):38. doi: 10.1186/1756-9966-33-38

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Copyright © 2014 Chen et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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AQP3 regulates EMT via the PI3K/AKT/Snail pathway. SGC7901and MGC803 cells were treated with control siRNA, RNAi AQP3 and EGF, with or without a PI3K/AKT inhibitor. Proteins were analyzed by western blotting assay. GAPDH was used as an internal control. The relative accumulation of proteins was compared with the untreated group.