Table 1.
Correlation between AQP3, E-cadherin,vimentin expression and clinicopathological features in GC
| Clinicopathological features | n |
AQP3 |
E-cadherin |
Vimentin |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| + | - | P-value | + | - | P-value | + | - | P-value | ||
| Age(yr) |
|
|
|
0.628 |
|
|
0.825 |
|
|
0.763 |
| ≤50 |
32 |
22 |
10 |
12 |
20 |
4 |
28 |
|||
| >50 |
57 |
43 |
14 |
23 |
34 |
10 |
47 |
|||
| Gender |
|
|
|
0.318 |
|
|
0.653 |
|
|
0.363 |
| Male |
58 |
40 |
18 |
24 |
34 |
11 |
47 |
|||
| Female |
31 |
25 |
6 |
11 |
20 |
3 |
28 |
|||
| Lauren classification |
|
|
|
0.008 |
|
|
0.659 |
|
|
0.015 |
| Intestinal |
54 |
34 |
20 |
20 |
34 |
4 |
50 |
|||
| Diffuse |
35 |
31 |
4 |
15 |
20 |
10 |
25 |
|||
| Tumor size |
|
|
|
0.303 |
|
|
0.816 |
|
|
0.758 |
| <3.0 cm |
28 |
18 |
10 |
10 |
18 |
5 |
23 |
|||
| ≥3.0 cm |
61 |
47 |
14 |
25 |
36 |
9 |
52 |
|||
| Tumor location |
|
|
|
0.515 |
|
|
0.920 |
|
|
0.880 |
| Upper third |
15 |
10 |
5 |
6 |
9 |
3 |
12 |
|||
| Middle third |
26 |
19 |
7 |
11 |
15 |
4 |
22 |
|||
| Lower third |
48 |
37 |
9 |
18 |
30 |
5 |
41 |
|||
| Depth of tumor invasion |
|
|
|
0.511 |
|
|
0.031 |
|
|
0.139 |
| Localized in subserosa |
38 |
13 |
25 |
20 |
18 |
3 |
35 |
|||
| Beyond subserosa |
51 |
22 |
29 |
15 |
36 |
11 |
40 |
|||
| Lymph node metastasis |
|
|
|
|
|
|
0.010 |
|
|
0.201 |
| N0 |
12 |
4 |
8 |
0.002 |
9 |
3 |
0 |
12 |
||
| N1–N3 |
77 |
61 |
16 |
26 |
51 |
14 |
63 |
|||
| Lymphovascular invasion |
|
|
|
0.044 | |
|
0.000 | |
|
0.004 |
| Absence |
58 |
38 |
20 |
32 |
26 |
4 |
54 |
|||
| Presence | 31 | 27 | 4 | 4 | 28 | 10 | 21 | |||