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. 2014 Mar 21;289(19):13142–13154. doi: 10.1074/jbc.M113.530311

FIGURE 1.

FIGURE 1.

SM and dihydrosphingosine changes in brain tissue after TBI. Sphingolipids were analyzed in brain tissue lysate made from the brain hemisphere ipsilateral to the injury imposed by a control cortical impact device as described under “Experimental Procedures.” Sham-injured animal brain was used as a control (con). A, total SM content was increased in the injured brain tissue. B and C, SM species changes in the injured tissue. D, dihydrosphingosine (DHsphingosine) was increased in the injured brain. Data are means ± S.E. (error bars); *, p < 0.05, n = 16. Each sample was normalized to its respective total protein levels.