TABLE 1.

Sequences of primers used for quantitative RT-PCR

Gene	Primer sequences
Human
GAPDH	Fwd 5′-GGA GTC AAC GGA TTT GGT CGT A-3′
	Rev 5′-CAA CAA TAT CCA CTT TAC CAG AGT TA-3′
MMP1	Fwd 5′-AGA TGA AAG GTG GAC CAA CAA TTT-3′
	Rev 5′-CCA AGA GAA TGG CCG AGT TC-3′
MMP2	Fwd 5′-TTG ATG GCA TCG CTC AGA TC-3′
	Rev 5′-TGT CAC GTG GCG TCA CAG T-3′
MMP9	Fwd 5′-CCA CCA CAA CAT CAC CTA TTG G-3′
	Rev 5′-GCA AAG GCG TCG TCA ATC A-3′
COX2	Fwd 5′-GAA TCA TTC ACC AGG CAA ATT G-3′
	Rev 5′-TCT GTA CTG CGG GTG GAA CA-3′
	Probe 6-FAM TCC TAC CAC CAG CAA CCC TGC CA 6-TAMRA
PAR1	Fwd 5′-CCG CCT GCT TCA GTC TGT-3′
	Rev 5′-ATC TAA GGT GGC ATT TGT TGC T-3′
Mouse
Cpha	Fwd 5′-GCT TTT CGC CGC TTG CT-3′
	Rev 5′-TCG TCA TCG GCC GTG AT-3′
Mmp2	Fwd 5′-GGA CTA TGA CCG GGA TAA GAA ATA TG-3′
	Rev 5′-GGG CAC CTT CTG AAT TTC CA-3′
Mmp9	Fwd 5′-AGA CCA AGG GTA CAG CCT GTT C-3′
	Rev 5′-GCA CGC TGG AAT GAT CTA AGC-3′
Mmp8	Fwd 5′-CAC ACA CAG CTT GCC AAT GC-3′
	Rev 5′-TTT CGT AGG TAA TTC TCA GCA GTT TTT-3′
Mmp13	Fwd 5′-GGC AAA AGC CAT TTC ATG CT-3′
	Rev 5′-TCT TCA TCG CCT GGA CCA TAA-3′
Cox1	Fwd 5′-TGCCCTCACCAGTCAATCC-3′
	Rev 5′-GTAGCCCGTGCGAGTACAATC-3′
Cox2	Fwd 5′-AGT TTG TTG AGT CAT TCA CCA GAC A-3′
	Rev 5′-CCA CTG CTT GTA CAG CAA TTG G-3′
Pgdh	Fwd 5′-TAG CAG GGC TCA TGC CTG TT-3′
	Rev 5′-TGG GCA AAT GAC ATT CAG TCT T-3′