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. 2014 Mar 20;289(19):13407–13418. doi: 10.1074/jbc.M113.530535

TABLE 5.

Summary of mutant analysis using both GlcA-containing and IdoA-containing substrates

Name of mutants Reactivity to compound 3 (GlcA-containing substrate) Reactivity to compound 4 (IdoA-containing substrate)
% %
2OST WT 100 100
2OST Y94A 23.0 35.7
2OST H106A 16.8 27.7
2OST R184A 10.1 8.3
2OST R189A 81.7 2.4
2OST K354A 82.0 101.2