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. 2014 Jan 31;12(2):288–341. doi: 10.2203/dose-response.13-035.Ristow

FIGURE 4.

FIGURE 4.

Overview on how ROS transcriptionally influence stress resistance and lifespan. High levels cause damage resulting in death of the cell and eventually the corresponding organism, whereas low levels are capable of activating transcription factors that mediate adaptive stress response culminating in increased lifespan.