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. 2014 May 8;9:110. doi: 10.1186/1748-717X-9-110

Table 2.

Univariate and multivariate analysis of prognostic factors for overall survival and distant failure

Variable
Median
Univariate
Multivariate analysis
  Survival time (months) Analysis P value Hazard ratio (95% CI) P value
Overall survival
 
 
 
 
Sex, male vs female
male (16.1); female (13.5)
0.1
 
 
Age (years), < 65 vs ≥ 65
< 65 (15.0); ≥ 65 (11.5)
0.1
 
 
KPS, ≤ 70 vs >70
≤ 70 (11.5); >70 (20.3)
0.001
0.30 (0.1-0.68)
0.01
Primary tumor, breast cancer vs others
breast cancer (13.0); others (15.5)
0.2
 
 
Extracranial metastases, absent vs present
absent (22.5); present (11.2)
0.0001
0.10 (0.05-0.40)
0.001
Number of metastases, 1 vs > 1
1 met (15.5); >1 met (13.2)
0.3
 
 
Distant brain failure
 
 
 
 
Sex, male vs female
male (16.1); female (13.5)
0.9
 
 
Age (years), < 65 vs ≥ 65
< 65 (12.0); ≥ 65 (10.0)
0.2
 
 
KPS, ≤ 70 vs >70
≤ 70 (8.0); >70 (16.0)
0.03
0.36 (0.16-1.27)
0.1
Primary tumor, breast cancer vs others
breast cancer (10.0); others (14.0)
0.1
 
 
Extracranial metastases, absent vs present
absent (18.0); present (8.0)
0.002
0.18 (0.07-0.64)
0.01
Number of metastases, 1 vs > 1 1 met (16.0); > 1 met (10.0) 0.1    

KPS, Karnofsky Performance Status.