TABLE 2.

Distribution of offspring's genotypes by mating between Impa1 Lys-95 heterozygotes

The abbreviations used are as follows: Wild, wild-type control; Het, heterozygote; and Homo, homozygote mice.

Stage		Wild	Het	Homo	Sum	χ2 test (df = 1)
Standard diet during pregnancy and lactation
E10.5	Observed	12	23	11	46	χ2 = 0.0435, p = 0.83
	Expected	11.5	23	11.5
E14.5	Observed	9	20	7a	36	χ2 = 0.0667, p = 0.41
	Expected	9	18	9
E18.5	Observed	68	136	30a,b	204	χ2 = 18.5, p = 1.69 × 10−5
	Expected	58.5	117	58.5
Weaning	Observed	30	53	1	84	χ2 = 25.8, p = 3.81 × 10−7
	Expected	21	42	21
Inositol supplementation during pregnancy and lactation
E18.5	Observed	8	26	12	46	χ2 = 1.48, p = 0.22
	Expected	11.5	23	11.5
Weaning	Observed	146	325	127	598	χ2 = 5.73, p = 0.017
	Expected	149.5	299	149.5

^a All fetuses/embryos show mandible hypoplasia.

^b Data include one dead fetus with a normal body size and mandible hypoplasia.