Table 1.
General Features of S. pyogenes Strains SSI-1, SF370, MGAS315, and MGAS8232
| Strains
|
||||
|---|---|---|---|---|
| Features | SSI-1 (M3) | SF370a(M1) | MGAS315b(M3) | MGAS8232c(M18) |
| Length of sequence (bp) | 1,894,275 | 1,852,441 | 1,900,521 | 1,895,017 |
| G+C content | 37.93% | 38.51% | 38.6% | 38.5% |
| Open reading frames | ||||
| Percentage coding | 85.94% | 83.77% | 85.76% | 84.94% |
| Protein coding region | 1861 | 1696 | 1865 | 1845 |
| Average gene length (bp) | 853 | 915 | 874 | 872 |
| SNPs (per gene)d | ||||
| Average number of SNPs | — | 11.53 | 0.05 | 12.61 |
| Silent SNPs (sSNPs) | — | 6.40 | 0.02 | 7.26 |
| Coding SNPs (cSNPs) | — | 5.13 | 0.03 | 5.35 |
| RNA | ||||
| Ribosomal RNA | 5 | 6 | 6 | 6 |
| Transfer RNA | 57 | 60 | 60 | 60 |
| tmRNA | 1 | 1 | 1 | 2 |
| Transposon or IS | 21 | 17 | 22 | 25 |
| Phage-related | ||||
| Pro-phage | 6 | 4 | 6 | 5 |
| Remnant | 4 | 4 | 3 | 3 |
a,b,c
The genomic sequences of other S. pyogenes strains (SF370:AE004092, MGAS8232: AR009949 and MGAS315: AE014074) were obtained through the Web site of the NCBI, http://www.ncbi.nlm.nih.gov.
d
SNPs in orthologous genes of strain SSI-1 were compared with those of strains SF370, MGAS315, and MGAS8232.