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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Exp Neurol. 2014 Feb 19;255:38–48. doi: 10.1016/j.expneurol.2014.02.013

Figure 6. Exercise prevents SCI-induced redistribution of GFL-responsive afferents in the ipsilesional dorsal horn.

Figure 6

Representative section of the ipsilesional C7 dorsal horn of Naïve (G),SCI No Allodynia with 9 (A) or 37 d (D) survival, SCI Allodynia with 9 (B) or 37 d (E) survival and SCI + Exercise with 9 (C) or 37 d (F) survival. Proportional area of positively labeled tissue within the dorsal horn was determined across the C7 and C8 spinal cord. The average proportional areas for these regions of interest are represented in H. Significantly greater proportional area was labeled for Isolectin-B4, a marker of non-peptidergic c-fibers at both 9 and 37 dpi of the SCI Allodynia group (*p<.05 vs all other groups; dashed line indicates the proportional area of Isolectin-B4+ afferents in the dorsal horn of naïve rats). (I)The degree of afferent labeling predicted at-level allodynia of the ipsilesional forepaw (r2=0.52; p<.05).