Table 5.
Reported AEs in the included studies.
| Author Sample Size* (Int./Cont.) |
Condition | Intervention group | Control group |
|---|---|---|---|
| Reported “No AEs” for intervention group | |||
| Liu et al. 2011 [24] | CINV | No AEs occurred | No AEs occurred |
| Yang et al. 2011 [25] | CINV | No AEs occurred | NR |
| Chen 2007 [27] | CINV | No AEs occurred | NR |
| Xue 2005 [37] | QOL | No AEs occurred | NR |
| Shen 2009 [18] 23/25 |
Pain | No AEs occurred | Constipation (9), nausea and vomiting (6), dizziness (3) |
|
| |||
| Identical Drug Used for Both Groups | |||
| Liu 2010 [16] 28/19 |
Pain | Nausea and vomiting (1), headache and dizziness (2) Resolved after the end of treatment |
Nausea and vomiting (3), headache and dizziness (5), drowsiness and fatigue (2) Resolved after the end of treatment |
| Sui and Zhang 2009 [33] 25/22 |
Hiccup | Xerostomia (9) Resolved after the end of treatment |
Xerostomia (10) Resolved after the end of treatment |
| Tao et al. 2000 [29]** 160/160 |
CINV | Headache and dizziness (26), bloating and constipation (4), and diarrhea (6) Resolved after the end of treatment |
Headache and dizziness (33), bloating and constipation (9), and diarrhea (20) Resolved after the end of treatment |
| Yan et al. 1997 [36] 28/30 |
Fever | Local pain and limitation of lower limb movement (5) Resolved after the end of treatment |
Insomnia and increased talkativeness (8) and panhidrosis (2) Did not affect further treatment |
|
| |||
| Different Drugs Used for Each Groups | |||
| Wang et al. 2004a*** [20] | Pain | Xerostomia, hot flashes, and blurred vision Relieved spontaneously |
Nausea, vomiting, constipation, and urinary retention Mild and tolerable level |
| Wang et al. 2004b*** [21] | Pain | Xerostomia, hot flashes, and blurred vision Relieved spontaneously Temporary low blood sugar Continued treatment after glucose IV injection or a meal |
Nausea, vomiting, constipation, and urinary retention Mild and tolerable level |
| Tao et al. 2000 [29]** 160/160 |
CINV | Headache and dizziness (26), bloating and constipation (4), and diarrhea (6) Resolved after the end of treatment |
Headache and dizziness (29), bloating and constipation (22), and diarrhea (5) Resolved after the end of treatment |
AEs: adverse events; CINV: chemotherapy-induced nausea and vomiting; Cont.: control group; Int.: intervention group; IV: intravenous; NR: not reported; QOL: quality of life.
Number in the parenthesis is reported number of cases.
*Sample size is reported on this table for studies with numerical data only.
**Two different control groups yielded two separate documentations in this table.
***Number of cases for symptoms were not reported.