Table 2.

Second-generation antipsychotics and the risk of metabolic abnormalities [47, 49].

Drug	Weight gain	Risk for diabetes mellitus	Worsening lipid profile
Clozapine	+++	+	+
Olanzapine	+++	+	+
Risperidone	++	D	D
Quetiapine	++	D	D
Aripiprazole*	+/−	−	−
Ziprasidone*	+/−	−	−

+: increase effect; −: no effect; D: discrepant results; *newer drugs with limited data.