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Light-dependent Cbl-cAMP-mediated rearrangement of actin cytoskeleton in rat embryonic fibroblasts (REF-52). Ref-52s were exposed to Cbl-cAMP, illuminated at 530 nm, and stained with Dylight 488-phalloidin to visualize the actin stress fibers. (a) No treatment, media alone (b) CPT-cAMP as a positive control (c) Cbl-cAMP, no illumination (d) Cbl-cAMP with illumination. Images are representative of 10 – 20 cells.
