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Nicotine-evoked current density. Current density was determined by dividing the peak-evoked current in response to 300 μM nicotine by the membrane capacitance. Pooled data from neurons with fast and slow current indicate that the slow current density is significantly greater than that of the fast current. The proportion of neurons from wild type (WT) and ART-OE (OE) mice with evoked current that was either fast or slow is indicated above each bar.
