Table 1.

Benefits of NSAIDs for specific gynecological diagnoses and the type of methodology used to establish efficacy.

Medical Implementation	Efficacy	Methodology & References
Primary Dysmenorrhea	Highly efficient, up to 85% in pain reduction	RCT* [1,2,3,6]
Menorrhagia	30-40% in bleeding reduction	RCT [ 7,8,9,10]
Pain/heavy bleeding associated with intrauterine device (IUD)	Up to 82% pain reduction, up to 57% in bleeding reduction	RCT [12]
Pain associated with medical abortion	Up to 48% in pain reduction	RCT [ 13,14,15]
Infertility	10% reduction in premature ovulation	Retrospective study [18,19,20]
Tocolysis	Significant reduction in preterm deliveries. Relative Risk 0.21.	RCT [ 27,28]

*RCT=Randomized controlled ­studies.