Table 2.

The Numbers of Ubiquitination-Associated Proteins Encoded in Six Draft/Finished Eukaryotic Genomes, Categorized by InterPro Domains and Enzyme Class

Class	InterPro acc	Homo sapiens	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans	Schizosaccharomyces pombe	Saccharomyces cerevisiae
E1	IPR000594	14	13	11	9	9	8
	IPR000127	7	8	3	4	3	3
	IPR000011	2	4	1	1	2	2
Total E1		16	16	11	9	9	8
E2	IPR000608	53	61	32	25	14	15
E3	IPR001810	78	74	34	434	13	14
	IPR001373	10	9	7	10	4	5
	IPR000569	38	38	13	10	7	5
	IPR003126	7	8	6	6	3	2
	IPR001841	385	305	121	170	51	40
	IPR001232	6	3	8	26	2	2
	IPR003613	9	8	6	4	3	2
Total E3		527	442	189	657	82	68
DUB	IPR001578	4	5	5	3	2	1
	IPR001394	67	70	21	33	16	18
	IPR001607	14	21	5	6	6	4
Total DUB		74	78	27	39	20	20
N/A	IPR000626	69	82	27	30	17	9
	IPR000449	65	69	28	19	12	9
	IPR001012	19	17	8	5	5	7
	IPR003892	11	11	4	4	3	7
	IPR003903	30	19	8	7	6	7
	IPR004854	1	1	1	2	1	1
Total N/A		184	187	63	57	39	35
TOTAL		835	764	320	785	162	145

The N/A class contains proteins possessing domains that do not yet have well understood roles in the other four classes