Figure 1.
The acylation and deacylation reactions are shown for a generalized β-lactam antibiotic and a serine protease type enzyme. For the current work, the ENZ–OH is Ser62 in R61, and the β-lactam is benzylpenicillin.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.