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. 2014 Jun;20(6):925–931. doi: 10.3201/eid2006.130584

Table 2. Results of testing for 12 women who had positive Coxiella burnetii titers during pregnancy, Denmark*.

Pt and preg First sample
Last sample
Comments
Date collected† Titers
Date collected† Titers
IgM II IgM I IgG II IgG I IgM II IgM I IgG II IgG I
Pt 1
7 wk
2,048
8,000
1,024
512

38 wk
<64
<64
256
<128
Negative titers 6 mo before this preg
Pt 2
8 wk, after miscarriage
256
<64
256
128

7 wk, after extrauterine preg
512
128
512
512
Maximum titers after second miscarriage: IgG phase II, 4,096; IgG phase I, 2,048; IgM phase I, 512; IgM phase II, 256
Pt 3
3 wk
<64
<64
<128
512

33
<64
<64
128
1,024
First titers taken 2 mo before this preg: IgG phase I, 1,024. Maximum titers in preg week 9: IgG phase I, 4,096; IgG phase II, 256‡
Pt 4
10 wk
<64
<64
1,024
512

1 day postpartum
<64
<64
1,024
128
First titers taken 3 mo before this preg identical to titers from preg week 10§
Pt 5
Preg 1 9 wk <64 <64 256 512 38 wk <64 <64 256 256 First titers taken 6 mo before this preg: IgM phase II, <64; IgM phase I, <64; IgG phase II, 512; IgG phase I, 1,024§
Preg 2
12 wk
<64
<64
128
1,024

31 wk
<64
<64
512
1,024
§
Pt 6
13 wk
<64
<64
256
<128

At birth
<64
<64
128
<128
No titers available before this preg. Maximum titers in preg: IgG phase II, 256‡
Pt 7
8 wk
128
<64
4,096
<128

At birth
64
<64
512
<128
Titers positive 6 mo before this preg: IgM phase II, 128; IgM phase I, <64; IgG phase II, 2048; IgG phase I, <128§
Pt 8
Preg 1 12 wk 128 <64 512 256 26 wk 256 <64 1,024 256 Maximum titers in this preg: IgG phase II, 2,048‡
Preg 2
10 wk
<64
<64
256
128

26 wk
<64
<64
256
256
Maximum titers in this preg: IgG phase I, 1,024; IgG phase II, 1,024‡
Pt 9
Preg 1 10 wk <64 <64 256 <128 39 wk 64 <64 128 <128 Maximum titers in this preg: phase II IgG, 1,024‡
Preg 2
12 wk
<64
<64
256
<128

36 wk
<64
<64
256
<128
§
Pt 10
Preg 1 8 wk 512 <64 4,096 <128 36 wk <64 <164 256 <128 No titers available before this preg§
Preg 2
9 wk
<64
<64
128
<128

14 wk
<64
<64
<128
<128
§
Pt 11
7 wk
<64
<64
128
128

26 wk
256
256
512
<128
Titers positive 1 mo before this preg: IgM phase II, <64; IgM phase I, <64; IgG phase II, 1,024; IgG phase I, <128§
Pt 12 10 wk <64 <64 2,048 <128 37 wk <64 <64 1,024 1,024 Negative titers during preg 2 years earlier. Maximum titers in this preg: IgG phase II, 2,048

*See Table 1 for specific patient and outcome data. Pt, patient; preg, pregnancy; vet, veterinarian; NA, not applicable; IUGR, intrauterine growth restriction.
†Gestational week.
‡Remaining titers have not risen above/beyond values in beginning/end of pregnancy.
§No further rise of titers in this pregnancy; indicates that titers had not risen beyond values at beginning/end of pregnancy.