Table 2. Results of testing for 12 women who had positive Coxiella burnetii titers during pregnancy, Denmark*.
Pt and preg | First sample |
Last sample |
Comments | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Date collected† | Titers |
Date collected† | Titers |
||||||||||
IgM II | IgM I | IgG II | IgG I | IgM II | IgM I | IgG II | IgG I | ||||||
Pt 1 |
7 wk |
2,048 |
8,000 |
1,024 |
512 |
|
38 wk |
<64 |
<64 |
256 |
<128 |
Negative titers 6 mo before this preg |
|
Pt 2 |
8 wk, after miscarriage |
256 |
<64 |
256 |
128 |
|
7 wk, after extrauterine preg |
512 |
128 |
512 |
512 |
Maximum titers after second miscarriage: IgG phase II, 4,096; IgG phase I, 2,048; IgM phase I, 512; IgM phase II, 256 |
|
Pt 3 |
3 wk |
<64 |
<64 |
<128 |
512 |
|
33 |
<64 |
<64 |
128 |
1,024 |
First titers taken 2 mo before this preg: IgG phase I, 1,024. Maximum titers in preg week 9: IgG phase I, 4,096; IgG phase II, 256‡ |
|
Pt 4 |
10 wk |
<64 |
<64 |
1,024 |
512 |
|
1 day postpartum |
<64 |
<64 |
1,024 |
128 |
First titers taken 3 mo before this preg identical to titers from preg week 10§ |
|
Pt 5 | |||||||||||||
Preg 1 | 9 wk | <64 | <64 | 256 | 512 | 38 wk | <64 | <64 | 256 | 256 | First titers taken 6 mo before this preg: IgM phase II, <64; IgM phase I, <64; IgG phase II, 512; IgG phase I, 1,024§ | ||
Preg 2 |
12 wk |
<64 |
<64 |
128 |
1,024 |
|
31 wk |
<64 |
<64 |
512 |
1,024 |
§ |
|
Pt 6 |
13 wk |
<64 |
<64 |
256 |
<128 |
|
At birth |
<64 |
<64 |
128 |
<128 |
No titers available before this preg. Maximum titers in preg: IgG phase II, 256‡ |
|
Pt 7 |
8 wk |
128 |
<64 |
4,096 |
<128 |
|
At birth |
64 |
<64 |
512 |
<128 |
Titers positive 6 mo before this preg: IgM phase II, 128; IgM phase I, <64; IgG phase II, 2048; IgG phase I, <128§ |
|
Pt 8 | |||||||||||||
Preg 1 | 12 wk | 128 | <64 | 512 | 256 | 26 wk | 256 | <64 | 1,024 | 256 | Maximum titers in this preg: IgG phase II, 2,048‡ | ||
Preg 2 |
10 wk |
<64 |
<64 |
256 |
128 |
|
26 wk |
<64 |
<64 |
256 |
256 |
Maximum titers in this preg: IgG phase I, 1,024; IgG phase II, 1,024‡ |
|
Pt 9 | |||||||||||||
Preg 1 | 10 wk | <64 | <64 | 256 | <128 | 39 wk | 64 | <64 | 128 | <128 | Maximum titers in this preg: phase II IgG, 1,024‡ | ||
Preg 2 |
12 wk |
<64 |
<64 |
256 |
<128 |
|
36 wk |
<64 |
<64 |
256 |
<128 |
§ |
|
Pt 10 | |||||||||||||
Preg 1 | 8 wk | 512 | <64 | 4,096 | <128 | 36 wk | <64 | <164 | 256 | <128 | No titers available before this preg§ | ||
Preg 2 |
9 wk |
<64 |
<64 |
128 |
<128 |
|
14 wk |
<64 |
<64 |
<128 |
<128 |
§ |
|
Pt 11 |
7 wk |
<64 |
<64 |
128 |
128 |
|
26 wk |
256 |
256 |
512 |
<128 |
Titers positive 1 mo before this preg: IgM phase II, <64; IgM phase I, <64; IgG phase II, 1,024; IgG phase I, <128§ |
|
Pt 12 | 10 wk | <64 | <64 | 2,048 | <128 | 37 wk | <64 | <64 | 1,024 | 1,024 | Negative titers during preg 2 years earlier. Maximum titers in this preg: IgG phase II, 2,048 |
*See Table 1 for specific patient and outcome data. Pt, patient; preg, pregnancy; vet, veterinarian; NA, not applicable; IUGR, intrauterine growth restriction. †Gestational week. ‡Remaining titers have not risen above/beyond values in beginning/end of pregnancy. §No further rise of titers in this pregnancy; indicates that titers had not risen beyond values at beginning/end of pregnancy.